About BSCM2TDb

Subclinical mastitis (SCM) is inflammation of the mammary gland that does not create visible changes in the milk or the udder. It affects the dairy industry by reducing milk production, decreasing milk quality, and suppressing reproductive performance (Khan and Khan, 2006; Ahmad et al., 2011). In India, the annual loss due to bovine mastitis at present is estimated to the tune of Rs. 71651.5 millions/year (Sudhan and Sharma, 2010; Rao et al., 2017). Apart from economic losses, subclinical mastitis has distinct importance in public health due to risk of antibiotic resistance. A study was performed to understand the role of epigeneic regulation of genes due to modified DNA methylation during SCM in water buffalo.
       BSCM2TDb contain the data generated from this study which included differential DNA methylation extracted from MeDIP-seq data of SCM group in comparison to healthy group in the form of differentially methylated regions (DMRs) and differentailly methylated genes (DMGs) along with differential gene expression extracted from RNA-seq data of same SCM group in comparison to healthy group in the form of differentially expressed genes (DEGs). Diffrentially methylated-differentiallty expressed genes (DM-DEGs) were also extracted, while comparing DNA methylation with gene expression. Additionally, KEGG pathways associated with DMGs (KEGG-DMGs), differentially methylated transposable elements (DM-TEs) along with differentially methylated transposable element associted genes (DM-TAGs) were also added along with methylated miRNAs and lncRNAs transcribed from methylated miRNA and lncRNA genes having DMR specific to subclinical mestitis (SCM).